This study projects land cover probabilities under climate change for corn (maize), soybeans, spring and winter wheat, winter wheat-soybean double cropping, cotton, grassland and forest across 16 central U.S. states at a high spatial resolution (see https://doi.pangaea.de/10.1594/PANGAEA.859593?format=html), while also taking into account the influence of soil characteristics and topography. The scenarios span three coupled climate models, three Representative Concentration Pathways (RCPs), and three time periods (2040, 2070, 2100). As climate change intensifies, the suitable area for all six crops display large northward shifts.